Kim YK, Yiu CK, Kim JR, Gu L, Kim SK, Weller RN, Pashley DH, Tay FR.
Source
Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea.
Abstract
Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Human dentin specimens were acid-etched, bonded with Fuji IX(GP), and immersed in a calcium-and-phosphate-containing 1.5X simulated body fluid (SBF) for 1-4 months. Polyacrylic acid and polyvinylphosphonic acid biomimetic analogs were added to the SBFs to create 2 additional remineralization media. Specimens were processed by transmission electron microscopy (TEM). No apatite deposition could be identified in the completely demineralized dentin in any of the specimens immersed in the 3 remineralization media, despite TEM/EDX evidence of diffusion of ions specific to the strontium-based GIC into the demineralized dentin. The hypothesis was rejected; mineral concentration alone is not a sufficient endpoint for assessing the success of contemporary remineralization strategies.
PMCID: PMC2826886 Free PMC Article
PMID: 20110510 [PubMed – indexed for MEDLINE]
1. J Dent Res. 2010 Mar;89(3):230-5. Epub 2010 Jan 28.